Bioactive C15 Acetogenins from the Red Alga Laurencia obtusa

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Isolaurenidificin and Bromlaurenidificin, Two New C15-Acetogenins from the Red Alga Laurencia obtusa.

Chromatographic fractionation of the CH₂Cl₂/MeOH extract of the Red Sea red alga Laurencia obtusa gave two new hexahydrofuro[3,2-b]furan-based C15-acetogenins, namely, isolaurenidificin (1) and bromlaurenidificin (2). The chemical structures were elucidated based on extensive analyses of their spectral data. Compounds 1 and 2 showed no toxicity (LC50 > 12 mM) using Artemia salina as test organi...

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Chemical Composition of Laurencia obtusa Extract and Isolation of a New C15-Acetogenin.

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 2011

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.59.1294