Bioactive C15 Acetogenins from the Red Alga Laurencia obtusa
نویسندگان
چکیده
منابع مشابه
Isolaurenidificin and Bromlaurenidificin, Two New C15-Acetogenins from the Red Alga Laurencia obtusa.
Chromatographic fractionation of the CH₂Cl₂/MeOH extract of the Red Sea red alga Laurencia obtusa gave two new hexahydrofuro[3,2-b]furan-based C15-acetogenins, namely, isolaurenidificin (1) and bromlaurenidificin (2). The chemical structures were elucidated based on extensive analyses of their spectral data. Compounds 1 and 2 showed no toxicity (LC50 > 12 mM) using Artemia salina as test organi...
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Two new chamigrane sesquiterpenes 1-2 and three known compounds 3-5 were isolated from a lipophilic extract of the red alga Laurencia dendroidea collected from the Southeastern Brazilian coast. Dendroidone (1) and dendroidiol (2) were isolated from samples collected at Biscaia Inlet, Angra dos Reis, Rio de Janeiro and at Manguinhos Beach, Serra, Espírito Santo, respectively. Debromoelatol (3), ...
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Chun-Shun Li, Xiao-Ming Li, Chuan-Ming Cui, and Bin-Gui Wang Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Nanhai Road 7, Qingdao 266071, P. R. China Reprint requests to Prof. Dr. Bin-Gui Wang. Fax: +86-532-82880645. E-mail: [email protected] Z. Naturforsch. 2010, 65b, 87 – 89; received October 10, 2009 One new sesquiterpenoid, aristolan...
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Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight previously known compounds isolated from the same samples. In particular, omaezol and hachijojim...
متن کاملChemical Composition of Laurencia obtusa Extract and Isolation of a New C15-Acetogenin.
A new C15-acetogenin, sagonenyne (20), exhibiting an unusual single tetrahydropyran ring was isolated from an ethyl acetate extract of Laurencia obtusa collected on the Corsican coastline. Its structure was established by detailed NMR spectroscopic analysis, mass spectrometry, and comparison with literature data. Twenty-three known compounds were identified in the same extract by means of colum...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2011
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.59.1294